alexisWhat does Alexis mean? A lexis as a boys' name (also used more widely as girls' name Alexis) is pronounced a-LEX-iss. It is of Greek orin, and the meaning of Alexis is defender. OftenThere are 40 Properties for Sale at Alexis. You can use our elegant Property Search Tool to find the rht HDB Flat, Condominium, Apartment, Executive Condominium, Terraced House,